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39th ECDD (2017) Agenda item 5.2 Cannabidiol (CBD) Page 8 of 27 oil or 41% yield as crystalline material. On a 100mmol scale, the yields were 46% as an oil, and 37% as crystalline material. [8] Figure 1: Synthesis of CBD with boron trifluoride (BF3)-etherate taken from Mechoulam et al 2002 [9] Synthesis of CBD in plants: